Children's Hospital Boston

Publications

Muglia LJ, Jacobson L, Majzoub JA. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature 1995; 373:427-432.

Hill AG, Jacobson L, Gonzalez J, Rounds J, Majzoub JA, Wilmore DW. Chronic central nervous system exposure to interleukin-1 beta causes catabolism in the rat. Am J Physiol 1996; 271:R1142-8.

Karalis K, Goodwin G, Majzoub JA. Cortisol blockade of progesterone: a possible molecular mechanism involved in the initiation of human labor. Nature Medicine 1996; 2:556-60.

Majzoub JA, Muglia LJ. Knockout mice. N Engl J Med 1996; 334:904-7.

Muglia L, Jacobson L, Majzoub JA. Production of corticotropin-releasing hormone-deficient mice by targeted mutation in embryonic stem cells. Ann NY Acad Sci 1996; 780:49-59.

Wolfl S, Martinez C, Rich A, Majzoub JA. Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation. Proc Natl Acad Sci USA 1996; 93:3664-8.

Fraefel C, Jacoby DR, Lage C, Hilderbrand H, Chou JY, Alt FW, Breakefield XO, Majzoub JA. Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors. Molec Med 1997; 3:813-25.

Gordon MS, Majzoub JA, Williams GH, Gordon MB. Sodium balance modulates thirst in normal man. Endocrine Res 1997; 23:377-92.

Iwasaki Y, Oiso Y, Saito H, Majzoub JA. Positive and negative regulation of the rat vasopressin gene promoter. Endocrinology 1997; 138:5266-74.

Jacobson L, Zurakowski D, Majzoub JA. Protein malnutrition increases plasma adrenocorticotropin and anterior pituitary pro-opiomelanocortin messenger ribonucleic acid in the rat. Endocrinology 1997; 138:1048-57.

Karalis K, Muglia LJ, Bae D, Hilderbrand H, Majzoub JA. CRH and the immune system. J Neuroimmunol 1997; 72:131-6.

Muglia LJ, Jacobson L, Weninger SC, Luedke CE, Bae DS, Jeong KH, Majzoub JA. Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice. J Clin Invest 1997; 99:2923-9.

Emanuel RL, Iwasaka Y, Arbiser Z, Velez EM, Emerson CH, Majzoub JA. Protein kinase A regulates vasopressin messenger RNA at both transcriptional and post-transcriptional levels. Endocrinology 1998; 139:2831-2837.

Gordon C, Majzoub JA, Marsh DJ, Mulliken JB, Ponder BA, Robinson BG, Eng C. Four cases of mucosal neuroma syndrome: multiple endocrine neoplasm 2B or not 2B? J Clin Endocrinol Metabol 1998; 83:17-20.

Grant FD, Ahmadi A, Hosley CM, Majzoub JA. Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant. J Clin Endocrinol Metabol 1998; 83:3958-64.

Hanley K, Feingold KR, Komuves LG, Elias PM, Muglia LJ, Majzoub JA, Williams ML. Glucocorticoid deficiency delays stratum corneum maturation in the fetal mouse. J Invest Dermatol 1998; 111:440-4.

Arbiser JA, Karalis K, Wiswanathan A, Kokke C, Anand-Apte, Zetter B, Majzoub JA. Angiogenic properties of corticotropin-releasing hormone. J Invest Dermatol 1999; 113:838-842.

Jeong KH, Jacobson L, Widmaier EP, Majzoub JA. Normal suppression of the reproductive axis following stress in corticotropin-releasing hormone-deficient mice. Endocrinology 1999; 140:1702-8.

Lopez MF, Dikkes P, Zurakowski D, Villa-Komaroff L, Majzoub JA. Regulation of hepatic glycogen in the insulin-like growth factor II-deficient mouse. Endocrinology 1999; 140:1442-8.

Ludwig DS, Majzoub JA, Al-Zahrani A, Dallal G, Blanco I, Roberts SB. High glycemic index foods, overeating, and obesity. Pediatrics 1999;103:1-6.

Majzoub JA, Karalis K. Placental corticotropin-releasing hormone: Function and regulation. Am J Obstet Gynecol 1999; 180:242-246.

Majzoub JA, McGregor JA, Lockwood CJ, Smith R, Taggart MS, Schulkin J. Toward a central theory of preterm and term labor: A putative role for corticotropin-releasing hormone. Am J Obstet Gynecol 1999; 180:232-241.

Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA. Proliferation and differentiation defects during lung epithelium development in corticotropin-releasing hormone deficient mice. Am J Resp Cell Mol Biol 1999; 20:181-188.

Venihaki M, Majzoub JA. Animal models of CRH deficiency. Frontiers in Neuroendocrinol 1999; 20:122-45.

Weninger SC, Dunn AJ, Muglia LJ, Dikkes P, Miczek KA, Swiergiel AH, Berridge CW, Majzoub JA. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH. Proc Natl Acad Sci USA 1999; 96:8283-8.

Weninger SC, Muglia LJ, Jacobson L, Majzoub JA. CRH is not required for decreases in food intake during chronic stress. Regulatory Peptides 1999; 84:69-74.

Wölfl S, Martinez C, Majzoub JA. Inducible binding of CREB to a cAMP-responsive promoter in vivo. Molec Endocrinology 1999; 13:659-669.

Jeong KH, Jacobson L, Pacák K,, Widmaier E, Goldstein DS, Majzoub JA. Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice. Endocrinology 2000; 141: 1142-1150.

Weninger SC, Peters LL, Majzoub JA. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and CRH deficiency. Endocrinology 2000; 141: 256-263.

Gudmundsson K, Majzoub JA, Bradwin G, Mandel S, Rifai N. Virilising 21-hydroxylase deficiency: Timing of newborn screening and confirmatory tests can be crucial. J Pediatr Endocrinol Metab 2000; in press.

Gordon CM, Dougherty DD, Rauch SL, Emans SJ, Grace E, Lamm R, Alpert N, Majzoub JA, Fischman AJ. Neuroanatomy of appetitive function in the human brain: A PET investigation. Internat J Eating Disorders 2000; in press.

Iwasaki Y, Majzoub JA. Disordered water metabolism: New insights from molecular diagnosis. In: Rogol A. ed. Current Opinion in Endocrinology and Diabetes. Philadelphia: Lippincott Williams & Wilkins 2000; in press.

Jacobson L, Muglia L, Weninger S, Pacak K, and Majzoub JA. CRH deficiency impairs but does not block pituitary-adrenal responses to diverse stressors. Neuroendocrinology 2000; in press.

Karalis K, Kontopoulos E, Muglia LJ, Majzoub JA. Proinflammatory action of epinephrine revealed by corticotropin-releasing hormone deficiency. Proc Natl Acad Sci USA 2000; in press.

Venichaki M, Majzoub JA. Insights from the corticotropin releasing hormone knockout mouse. Frontiers in Neuroendocinology 2000; in press.

Weninger S, Majzoub JA. Corticotropin-releasing hormone regulation of the hypothalamic-pituitary-adrenal axis. In: McEwen B. ed. Handbook of Physiology: Coping with the Environment. NY: Oxford University Press, 2000; in press.

See Dr. Majzoub's publications via PubMed




		Publications Muglia LJ, Jacobson L, Majzoub JA. Corticotropin-releasing hormone deficiency reveals major fetal but not adult glucocorticoid need. Nature 1995; 373:427-432. Hill AG, Jacobson L, Gonzalez J, Rounds J, Majzoub JA, Wilmore DW. Chronic central nervous system exposure to interleukin-1 beta causes catabolism in the rat. Am J Physiol 1996; 271:R1142-8. Karalis K, Goodwin G, Majzoub JA. Cortisol blockade of progesterone: a possible molecular mechanism involved in the initiation of human labor. Nature Medicine 1996; 2:556-60. Majzoub JA, Muglia LJ. Knockout mice. N Engl J Med 1996; 334:904-7. Muglia L, Jacobson L, Majzoub JA. Production of corticotropin-releasing hormone-deficient mice by targeted mutation in embryonic stem cells. Ann NY Acad Sci 1996; 780:49-59. Wolfl S, Martinez C, Rich A, Majzoub JA. Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation. Proc Natl Acad Sci USA 1996; 93:3664-8. Fraefel C, Jacoby DR, Lage C, Hilderbrand H, Chou JY, Alt FW, Breakefield XO, Majzoub JA. Gene transfer into hepatocytes mediated by helper virus-free HSV/AAV hybrid vectors. Molec Med 1997; 3:813-25. Gordon MS, Majzoub JA, Williams GH, Gordon MB. Sodium balance modulates thirst in normal man. Endocrine Res 1997; 23:377-92. Iwasaki Y, Oiso Y, Saito H, Majzoub JA. Positive and negative regulation of the rat vasopressin gene promoter. Endocrinology 1997; 138:5266-74. Jacobson L, Zurakowski D, Majzoub JA. Protein malnutrition increases plasma adrenocorticotropin and anterior pituitary pro-opiomelanocortin messenger ribonucleic acid in the rat. Endocrinology 1997; 138:1048-57. Karalis K, Muglia LJ, Bae D, Hilderbrand H, Majzoub JA. CRH and the immune system. J Neuroimmunol 1997; 72:131-6. Muglia LJ, Jacobson L, Weninger SC, Luedke CE, Bae DS, Jeong KH, Majzoub JA. Impaired diurnal adrenal rhythmicity restored by constant infusion of corticotropin-releasing hormone in corticotropin-releasing hormone-deficient mice. J Clin Invest 1997; 99:2923-9. Emanuel RL, Iwasaka Y, Arbiser Z, Velez EM, Emerson CH, Majzoub JA. Protein kinase A regulates vasopressin messenger RNA at both transcriptional and post-transcriptional levels. Endocrinology 1998; 139:2831-2837. Gordon C, Majzoub JA, Marsh DJ, Mulliken JB, Ponder BA, Robinson BG, Eng C. Four cases of mucosal neuroma syndrome: multiple endocrine neoplasm 2B or not 2B? J Clin Endocrinol Metabol 1998; 83:17-20. Grant FD, Ahmadi A, Hosley CM, Majzoub JA. Two novel mutations of the vasopressin gene associated with familial diabetes insipidus and identification of an asymptomatic carrier infant. J Clin Endocrinol Metabol 1998; 83:3958-64. Hanley K, Feingold KR, Komuves LG, Elias PM, Muglia LJ, Majzoub JA, Williams ML. Glucocorticoid deficiency delays stratum corneum maturation in the fetal mouse. J Invest Dermatol 1998; 111:440-4. Arbiser JA, Karalis K, Wiswanathan A, Kokke C, Anand-Apte, Zetter B, Majzoub JA. Angiogenic properties of corticotropin-releasing hormone. J Invest Dermatol 1999; 113:838-842. Jeong KH, Jacobson L, Widmaier EP, Majzoub JA. Normal suppression of the reproductive axis following stress in corticotropin-releasing hormone-deficient mice. Endocrinology 1999; 140:1702-8. Lopez MF, Dikkes P, Zurakowski D, Villa-Komaroff L, Majzoub JA. Regulation of hepatic glycogen in the insulin-like growth factor II-deficient mouse. Endocrinology 1999; 140:1442-8. Ludwig DS, Majzoub JA, Al-Zahrani A, Dallal G, Blanco I, Roberts SB. High glycemic index foods, overeating, and obesity. Pediatrics 1999;103:1-6. Majzoub JA, Karalis K. Placental corticotropin-releasing hormone: Function and regulation. Am J Obstet Gynecol 1999; 180:242-246. Majzoub JA, McGregor JA, Lockwood CJ, Smith R, Taggart MS, Schulkin J. Toward a central theory of preterm and term labor: A putative role for corticotropin-releasing hormone. Am J Obstet Gynecol 1999; 180:232-241. Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA. Proliferation and differentiation defects during lung epithelium development in corticotropin-releasing hormone deficient mice. Am J Resp Cell Mol Biol 1999; 20:181-188. Venihaki M, Majzoub JA. Animal models of CRH deficiency. Frontiers in Neuroendocrinol 1999; 20:122-45. Weninger SC, Dunn AJ, Muglia LJ, Dikkes P, Miczek KA, Swiergiel AH, Berridge CW, Majzoub JA. Stress-induced behaviors require the corticotropin-releasing hormone (CRH) receptor, but not CRH. Proc Natl Acad Sci USA 1999; 96:8283-8. Weninger SC, Muglia LJ, Jacobson L, Majzoub JA. CRH is not required for decreases in food intake during chronic stress. Regulatory Peptides 1999; 84:69-74. Wölfl S, Martinez C, Majzoub JA. Inducible binding of CREB to a cAMP-responsive promoter in vivo. Molec Endocrinology 1999; 13:659-669. Jeong KH, Jacobson L, Pacák K,, Widmaier E, Goldstein DS, Majzoub JA. Impaired basal and restraint-induced epinephrine secretion in corticotropin-releasing hormone-deficient mice. Endocrinology 2000; 141: 1142-1150. Weninger SC, Peters LL, Majzoub JA. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and CRH deficiency. Endocrinology 2000; 141: 256-263. Gudmundsson K, Majzoub JA, Bradwin G, Mandel S, Rifai N. Virilising 21-hydroxylase deficiency: Timing of newborn screening and confirmatory tests can be crucial. J Pediatr Endocrinol Metab 2000; in press. Gordon CM, Dougherty DD, Rauch SL, Emans SJ, Grace E, Lamm R, Alpert N, Majzoub JA, Fischman AJ. Neuroanatomy of appetitive function in the human brain: A PET investigation. Internat J Eating Disorders 2000; in press. Iwasaki Y, Majzoub JA. Disordered water metabolism: New insights from molecular diagnosis. In: Rogol A. ed. Current Opinion in Endocrinology and Diabetes. Philadelphia: Lippincott Williams & Wilkins 2000; in press. Jacobson L, Muglia L, Weninger S, Pacak K, and Majzoub JA. CRH deficiency impairs but does not block pituitary-adrenal responses to diverse stressors. Neuroendocrinology 2000; in press. Karalis K, Kontopoulos E, Muglia LJ, Majzoub JA. Proinflammatory action of epinephrine revealed by corticotropin-releasing hormone deficiency. Proc Natl Acad Sci USA 2000; in press. Venichaki M, Majzoub JA. Insights from the corticotropin releasing hormone knockout mouse. Frontiers in Neuroendocinology 2000; in press. Weninger S, Majzoub JA. Corticotropin-releasing hormone regulation of the hypothalamic-pituitary-adrenal axis. In: McEwen B. ed. Handbook of Physiology: Coping with the Environment. NY: Oxford University Press, 2000; in press. See Dr. Majzoub's publications via PubMed