Children's Hospital Boston is one of three Harvard-affiliated organizations that have joined with Roche in a new partnership aimed at identifying new drugs for autism spectrum disorders (ASDs) using induced pluripotent stem cells from ASD patients. (Image: Miserlou/Wikimedia Commons) [Read more]
According to Zoltan Szallasi, MD, of Boston Children's Hospital's Informatics Program (CHIP), measuring the total amount of DNA damage within a tumor’s cells—as opposed to looking for mutations in just one or two genes—could help doctors predict its vulnerability to chemotherapy drugs like cisplatin. [Read more]
Judy Lieberman, PhD, in the Program in Cellular and Molecular Medicine at Boston Children's Hospital and the Immune Disease Institute (PCMM/IDI) and colleagues have developed a molecular delivery platform that overcomes one of the biggest obstacles to using RNA-based gene silencing technologies to treat cancer: making sure the treatment gets to the right place and stays there. [Read more]
David Clapham, MD, PhD, chief of the Basic Cardiovascular Research Laboratories at Boston Children’s Hospital, thinks that interfering with a gate-like protein called Hv1 could curb the inflammatory aftermath of a stroke, something that existing drugs cannot do. [Read more]
Check out our timeline of Recent Advances and Featured Science and Innovations.
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